How to Fix Recurring Treatment Resistant Intestinal Yeast Overgrowth

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How to Treat Chronic Recurrent Treatment Resistant Intestinal Yeast Overgrowth Image

Weed, Seed, and Feed for Chronic Recurring Intestinal Yeast Overgrowth

Due to antibiotic herbs and prescriptions used to treat Lyme, some people develop very difficult to treat intestinal yeast overgrowth once Lyme and related infections are in remission or eliminated. Such people may try repeated rounds of anti-yeast medications, only to have the intestinal yeast recur again and again. In this video article, Marty Ross, MD explains how to stop this problem using a "weed, seed, and feed" approach. 

for more information about intestinal yeast overgrowth treatment and prevention see Kills & Prevents Yeast: A Brief Guide.

Marty Ross MD Discusses How to Stop
Treatment Resistant Intestinal Overgrowth

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Weed out Intestinal Yeast

When people have recurring yeast infections after treating Lyme, sometimes it is necessary to agressively kill the intestinal yeast with Amphoterecin B. I resort to using Amphoterecin B when standard herbal medicine and prescription medicine options like fluconazole (Diflucan), itraconazole (Sporonax), and terbinafine (Lamisil) do not work. 

  • Amphoterecin B 200 mg to 250 mg 1 pill 3 times a day for 2 to 4 months. This prescription medication is made by a compounding pharmacy.

After stopping the Amphoterecin B, prevent yeast from popping up again for an additional 8 to 10 months using weaker anti-yeast prescriptions or herbs.

  • Nystatin 500,000 IU 2 pills 2 times a day ongoing while on herbal or prescription antibiotics. A person can replace nystatin with an herbal combination mixture 2 pills 2 times a day. (Common herbs found individually or mixed together that promote yeast removal include: Pau D’arco, caprylic acid, rosemary oil, thyme oil, garlic, and grapefruit seed extract. Products I recommend which include some of these herbs include: CapriPlus by Karuna and Phytostan by Integrative Therapeutics.)

Seed The Intestines with Healthy Bacteria

Option 1

Use a spore-forming soil-based probiotic product and a separate human intestinal strain product.

  • Spore-Forming Probiotic. In my practice I use the following products. Corebiotic by Researched Nutritionals 2 to 4 pills 1 time a day. This product is a soil-based spore-forming probiotic that includes strains of Bacillus scientifically proven to support intestinal health. Consider using Corebiotic Sensitive, which does not include prebiotic fiber, if Corebiotic causes gassiness. Another spore-forming probiotic to consider is Proflora R by Bio-botanical Research. These products do not require refrigeration.
  • Human-Strain Probiotic. In my practice I use HMF Forte Shelf Stable by Genestra 2 to 4 pills 1 time a day. This product includes human strains. This product does not require refrigeration.

Option 2

Use a combination product that includes spore-forming soil-based probiotics with human intestinal strain probiotics.

  • Combation Spore-Forming Probiotic and Human-Strain Probiotic. In my practice I use Multi-Biome by Researched Nutritionals 2 to 4 pills 1 time a day. This product does not require refrigeration.

Feed Healthy Bacteria and Starve Intestinal Yeast

Sometimes you have to feed the good bacteria in the intestines so they can keep yeast under control. I recommend adding steps to feed healthy intestinal bacteria when a person has recurrent and difficult-to-treat intestinal yeast infections. Additionally, limiting simple sugars and carbs to starve yeast helps.

One of the best food sources for healthy intestinal yeast is soluble fiber. Food sources of low-carb (sugar) soluble fiber include avocados, soy nuts, ​oat bran, ​brussels sprouts, ​sweet potato, ​asparagus​ and broccoli. Another option to increase soluble fiber is to take modified citrus pectin powder 1 scoop one or two times a day.


The ideas and recommendations on this website and in this article are for informational purposes only. For more information about this, see the sitewide Terms & Conditions.


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About The Author

Marty Ross, MD is a passionate Lyme disease educator and clinical expert. He helps Lyme sufferers and their physicians see what really works based on his review of the science and extensive real-world experience. Dr. Ross is licensed to practice medicine in Washington State (License: MD00033296) where he has treated thousands of Lyme disease patients in his Seattle practice.

Marty Ross, MD is a graduate of Indiana University School of Medicine and Georgetown University Family Medicine Residency. He is a member of the International Lyme and Associated Disease Society (ILADS), The Institute for Functional Medicine, and The American Academy of Anti-Aging Medicine (A4M).

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