Transfer Factors: Turn On The Army

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What Are Transfer Factors?

Transfer factors may boost the immune system when someone is not getting better or may help prevent relapse of borrelia (Lyme), bartonella, and babesia. In this article I describe the important role of transfer factors and how to take them in a Lyme disease treatment as an immune system support.

I like to divide the immune system into two parts to describe transfer factors. These parts are the detectives and the army.


This is the part of the immune system that can identify bacteria and viruses and tell the army which cells contain them. But the detectives do not fight. They turn on the army to fight the battle.

The detectives include a type of white blood cell called a phagocyte and another type of white blood cell called a CD 4 T Helper. Phagocytes see infected cells. They present these cells to the CD-4 T Helper cells and turn them on with inflammation chemicals called cytokines. The CD-4 T Helper cells then make transfer factors. Transfer factors bind to cells containing the viruses. Effectively the transfer factors communicate to the army which cells should be attacked.

Transfer Factors in Lyme disease treatment image from Marty Ross MD

The Army

The army is the part of the immune system that attacks a germs. This includes CD 8 Killer T cells. These cells are turned on by the detectives using cytokines. They attack cells marked with transfer factors by the detectives.

Marty Ross MD Discusses Transfer Factors

This video was recorded during Conversations with Marty Ross MD in July 2018 while Dr. Ross practiced in Seattle, Washington.

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Targeted Transfer Factors

Germ specific transfer factors target the army. These are called targeted transfer factors. So there are separate transfer factors for borrelia (lyme) and others for the co-infection bartonella. There are transfer factors against the flu virus and also against cold viruses. In my practice in Seattle I used transfer factors made by Researched Nutritionals.

Targeted Transfer Factors

  • Transfer Factor L Plus. This product includes transfer factors against borrelia, bartonella, babesia, ehrlicia, EBV, HHV6, CMV, and chlamydia pneumoniae.
  • Transfer Factor Plasmyc. This product contains transfer factors against borrelia, EBV, HHV6, CMV, chlamydia pneumoniae, pneumocystis carinii, tuberculosis, herpes type 1, herpes type 2, cryptosporosis, mycobacteriam avian, hepatitis A, B, C, staphloccoci, streptococci, e. coli, parvovirus B19, varicella zoster, candida, mumps, measles, rubella, mycoplasma, ureaplasma, nanobacterium, and human papilloma viruses.
  • Transfer Factor Enviro. This product includes transfer factors against mold toxins made by candida, penicillum, epicoccum, aspergillus fumigatus, aspergillus niger, aspergillus versicolor, cladisporium, fusarium, geotrichum, pithomyces, and ustilago.

General Transfer Factors

Finally there are general mixes of transfer factors that are not specific for any type of germ. These transfer factors generally turn on the Natural Killer T cells to fight any type of infection.

  • Transfer Factor Multi-immune
  • Transfer Factor Multi-immune mushroom free
  • Transfer Factor Sensitive

Dosing Transfer Factors 

Start each at 1 pill 1 time a day and in 7 days increasing to 1 pill 2 times a day. For information about treating chronic virus infections see: Kills Viruses: A Brief Guide. For information about Lyme relapse prevention see: Finished? And How to Prevent Relapse.


The ideas and recommendations on this website and in this article are for informational purposes only. For more information about this, see the sitewide Terms & Conditions.


View Citations

  1. White, A. A guide to transfer factors & immune system health. North Charleston, South Carolina: BookSurge Publishing; 2009.
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About The Author

Marty Ross, MD is a passionate Lyme disease educator and clinical expert. He helps Lyme sufferers and their physicians see what really works based on his review of the science and extensive real-world experience. Dr. Ross is licensed to practice medicine in Washington State (License: MD00033296) where he has treated thousands of Lyme disease patients in his Seattle practice.

Marty Ross, MD is a graduate of Indiana University School of Medicine and Georgetown University Family Medicine Residency. He is a member of the International Lyme and Associated Disease Society (ILADS), The Institute for Functional Medicine, and The American Academy of Anti-Aging Medicine (A4M).

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